RBMO publishes study showing that Covid-19 vaccine doesn’t affect fertility treatments
January, 26th 2023
The possible implication of double vaccination against Covid-19 in patients undergoing fertility treatment has been one of the questions the scientific community and patients have been asking since the pandemic outbreak. To dispel the uncertainty generated by an unknown and new situation, researchers at the Bernabeu Institute have developed a novel study to test whether having two doses of the vaccine has any effect on ovarian stimulation and embryo development in the laboratory.
In this case, the study was conducted in egg donors and compared the cycles before and after receiving the doses. The results are reassuring, as no changes that could be in detrimental to assisted reproduction treatments outcome in young people have been observed.
Now, this research entitled Oocyte donors and mRNA Covid-19 vaccination: Is there any impact on ovarian stimulation parameters or in IVF outcomes for recipients? has been published in the international scientific journal Reproductive BioMedicine Online (RBMO).
The main objective of the researchers was to show the effect vaccination could have on parameters such as days of ovarian stimulation, gonadotropin dose, the number of oocytes obtained after ovarian puncture and the mature oocyte ratio. In addition, the effects on other values related to the IVF laboratory such as fertilisation rate, embryo development and clinical gestation rate have also been studied.
“According to our results, there is no adverse influence of vaccination on fertilisation, embryo development and pregnancy rates in oocyte recipients. We found that results with and without vaccination are not significantly different,” explains embryologist Aranzazu Bosch, one of the study’s principal investigators.
The importance of this finding is justified by the fact that it offers total security and peace of mind to both patients undergoing in vitro fertilisation and recipients of donated oocytes, because they can be sure the results of their cycles will not be affected by the Covid vaccine.
This is the first study carried out at Instituto Bernabeu related to the implication of vaccination which, in addition, expands on other international researches carried out.
A.Bosch; S. Albero; J. Castillo; J. Ten; J. Guerrero; J.A. Ortiz; A. Bernabeu; R. Bernabeu