A study by Instituto Bernabeu concludes that eggs from younger donors have lower aneuploidy rates

Dr Paula Moral, from Instituto Bernabeu, will present at the Spanish Fertility Society (SEF in Spanish) congress a study on the impact of donor age on embryonic aneuploidy. The study analyses data from more than 500 egg donation cycles in which PGT-A (Preimplantation Genetic Test for Aneuploidy) has been performed to determine the percentage of embryos with aneuploidy and its correlation with the age of the donors.

“This study was prompted by the controversy surrounding the results of previous work suggesting that younger oocyte donors might have poorer outcomes in oocyte donation cycles,” explains Dr Moral. “We have therefore conducted a retrospective analysis of our own data to obtain a definitive answer to this question.”

The study reveals that embryos from the youngest donors have the lowest rate of aneuploidy, a rate that predictably increases with age. “This finding is of great importance to couples who use oocyte donation as a fertility treatment,” says Dr Moral. “It gives them peace of mind to know that younger donors provide better quality embryos, which increases the chances of achieving a successful pregnancy.”