Megacolon

Abnormally large colon. It can be congenital or Hirschsprung’s disease due to the absence of nerve cells in the junction between the rectum and colon. The aganglionic area of the bowel cannot relax during bowel movements leading to constipation and colonic distention. In newborns, symptoms include abdominal distention, failure to pass meconium and vomiting bile.